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F199E substitution reduced toxicity of Clostridium perfringens epsilon toxin by depriving the receptor binding capability.
Kang, Jingjing; Gao, Jie; Yao, Wenwu; Kang, Lin; Gao, Shan; Yang, Hao; Ji, Bin; Li, Ping; Liu, Jing; Yao, Jiahao; Xin, Wenwen; Zhao, Baohua; Wang, Jinglin.
Affiliation
  • Kang J; a Life Science Institute of Hebei Normal University , Shijiazhuang, Hebei Province , PR China.
  • Gao J; a Life Science Institute of Hebei Normal University , Shijiazhuang, Hebei Province , PR China.
  • Yao W; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Kang L; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Gao S; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Yang H; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Ji B; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Li P; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Liu J; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Yao J; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Xin W; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
  • Zhao B; a Life Science Institute of Hebei Normal University , Shijiazhuang, Hebei Province , PR China.
  • Wang J; b State Key Laboratory of Pathogen and Biosecurity , Institute of Microbiology and Epidemiology , Beijing , PR China.
Hum Vaccin Immunother ; 13(7): 1598-1608, 2017 07 03.
Article in En | MEDLINE | ID: mdl-28304231
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Receptors, Cell Surface / Amino Acid Substitution / Mutant Proteins Limits: Animals / Humans Language: En Journal: Hum Vaccin Immunother Year: 2017 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Receptors, Cell Surface / Amino Acid Substitution / Mutant Proteins Limits: Animals / Humans Language: En Journal: Hum Vaccin Immunother Year: 2017 Document type: Article Country of publication: