A Novel Neuroprotective Small Molecule for Glial Cell Derived Neurotrophic Factor Induction and Photoreceptor Rescue.

Baranov, Petr; Lin, Hong; McCabe, Kathryn; Gale, David; Cai, Shenshen; Lieppman, Burke; Morrow, Dwight; Lei, Phoebe; Liao, Justin; Young, Michael

Baranov, Petr; Lin, Hong; McCabe, Kathryn; Gale, David; Cai, Shenshen; Lieppman, Burke; Morrow, Dwight; Lei, Phoebe; Liao, Justin; Young, Michael.

Affiliation

Baranov P; 1 The Schepens Eye Research Institute , Massachusetts Eye and Ear, an affiliate of Harvard Medical School, Boston, Massachusetts.
Lin H; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
McCabe K; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Gale D; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Cai S; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Lieppman B; 1 The Schepens Eye Research Institute , Massachusetts Eye and Ear, an affiliate of Harvard Medical School, Boston, Massachusetts.
Morrow D; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Lei P; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Liao J; 2 GlaxoSmithKline LLC , Philadelphia, Pennsylvania.
Young M; 1 The Schepens Eye Research Institute , Massachusetts Eye and Ear, an affiliate of Harvard Medical School, Boston, Massachusetts.

J Ocul Pharmacol Ther ; 33(5): 412-422, 2017 06.

Article in En | MEDLINE | ID: mdl-28441076

Subject(s)
Key words

GDNF; neuroprotection; photoreceptors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Degeneration / Neuroprotective Agents / Photoreceptor Cells, Vertebrate / Glial Cell Line-Derived Neurotrophic Factor / Small Molecule Libraries Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Ocul Pharmacol Ther Journal subject: FARMACOLOGIA / OFTALMOLOGIA / TERAPEUTICA Year: 2017 Document type: Article

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