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Measurement of 43Sc and 44Sc production cross-section with an 18MeV medical PET cyclotron.
Carzaniga, Tommaso Stefano; Auger, Martin; Braccini, Saverio; Bunka, Maruta; Ereditato, Antonio; Nesteruk, Konrad Pawel; Scampoli, Paola; Türler, Andreas; van der Meulen, Nicholas.
Affiliation
  • Carzaniga TS; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
  • Auger M; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
  • Braccini S; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland. Electronic address: saverio.braccini@lhep.unibe.ch.
  • Bunka M; Department of Chemistry and Biochemistry (DCB), University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
  • Ereditato A; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
  • Nesteruk KP; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland.
  • Scampoli P; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Department of Physics "E. Pancini", University of Naples Federico II, Compl
  • Türler A; Albert Einstein Center for Fundamental Physics (AEC), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland; Department of Chemistry and Biochemistry (DCB), University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland; Paul Scherrer Institut (PSI), Laboratory for Radiochemistry, CH-5232 Vi
  • van der Meulen N; Paul Scherrer Institut (PSI), Laboratory for Radiochemistry, CH-5232 Villigen, Switzerland.
Appl Radiat Isot ; 129: 96-102, 2017 Nov.
Article in En | MEDLINE | ID: mdl-28830022
ABSTRACT
43Sc and 44Sc are positron emitter radionuclides that, in conjunction with the ß- emitter 47Sc, represent one of the most promising possibilities for theranostics in nuclear medicine. Their availability in suitable quantity and quality for medical applications is an open issue and their production with medical cyclotrons represents a scientific and technological challenge. For this purpose, an accurate knowledge of the production cross sections is mandatory. In this paper, we report on the cross section measurement of the reactions 43Ca(p,n)43Sc, 44Ca(p,2n) 43Sc, 46Ti(p,α)43Sc, and 44Ca(p,n)44Sc at the Bern University Hospital cyclotron. A study of the production yield and purity performed by using commercially available enriched target materials is also presented.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2017 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2017 Document type: Article Affiliation country: