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MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB.
Cordas Dos Santos, David M; Eilers, Juliane; Sosa Vizcaino, Alfonso; Orlova, Elena; Zimmermann, Martin; Stanulla, Martin; Schrappe, Martin; Börner, Kathleen; Grimm, Dirk; Muckenthaler, Martina U; Kulozik, Andreas E; Kunz, Joachim B.
Affiliation
  • Cordas Dos Santos DM; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Children's Hospital, Heidelberg, Germany.
  • Eilers J; Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany.
  • Sosa Vizcaino A; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Children's Hospital, Heidelberg, Germany.
  • Orlova E; Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany.
  • Zimmermann M; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Children's Hospital, Heidelberg, Germany.
  • Stanulla M; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Heidelberg University Children's Hospital, Heidelberg, Germany.
  • Schrappe M; Department of Pediatric Hematology and Oncology, MH Hannover, Hannover, Germany.
  • Börner K; Department of Pediatric Hematology and Oncology, MH Hannover, Hannover, Germany.
  • Grimm D; Department of Pediatrics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Muckenthaler MU; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany.
  • Kulozik AE; German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.
  • Kunz JB; BioQuant Center, Heidelberg University, Heidelberg, Germany.
BMC Cancer ; 18(1): 663, 2018 Jun 18.
Article in En | MEDLINE | ID: mdl-29914415

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MAP Kinase Kinase Kinases / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2018 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MAP Kinase Kinase Kinases / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2018 Document type: Article Affiliation country: Country of publication: