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Shigella effector IpaH4.5 targets 19S regulatory particle subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.
Otsubo, Ryota; Mimuro, Hitomi; Ashida, Hiroshi; Hamazaki, Jun; Murata, Shigeo; Sasakawa, Chihiro.
Affiliation
  • Otsubo R; Department of infection Microbiology, Research Institute for Microbial Diseases, Osaka University, Suita City, Osaka, Japan.
  • Mimuro H; Department of infection Microbiology, Research Institute for Microbial Diseases, Osaka University, Suita City, Osaka, Japan.
  • Ashida H; Division of Bacteriology, Department of Infectious Diseases Control, International Research Center for infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Hamazaki J; Department of Bacterial pathogenesis, Infection and Host Response, Graduate of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Murata S; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
  • Sasakawa C; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Cell Microbiol ; 21(3): e12974, 2019 03.
Article in En | MEDLINE | ID: mdl-30414351
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shigella flexneri / Bacterial Proteins / T-Lymphocytes, Cytotoxic / Proteasome Endopeptidase Complex / Intracellular Signaling Peptides and Proteins / Host-Pathogen Interactions / Immune Evasion / Antigens, Bacterial Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shigella flexneri / Bacterial Proteins / T-Lymphocytes, Cytotoxic / Proteasome Endopeptidase Complex / Intracellular Signaling Peptides and Proteins / Host-Pathogen Interactions / Immune Evasion / Antigens, Bacterial Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication: