Sex differences in treatment and prognosis of acute coronary syndrome with interventional management.
Cardiovasc Revasc Med
; 20(3): 183-186, 2019 03.
Article
in En
| MEDLINE
| ID: mdl-30905407
ABSTRACT
OBJECTIVE:
Female sex has been associated with differences in diagnostic and management of acute coronary syndrome (ACS). Our aim was to analyze sex differences in ACS with interventional management in a tertiary care hospital.METHODS:
Patients with ACS admitted to a Spanish tertiary care referral center were included prospectively and consecutively. All patients included in the study underwent a coronary angiography.RESULTS:
From the total cohort of 1214 patients, 290 (24%) were women. Women were older (71⯱â¯12.8 vs 64⯱â¯13.4â¯years, pâ¯<â¯0.001) and showed lower ischemic risk and higher hemorrhagic risk scores (GRACE 159⯱â¯45 vs 171⯱â¯42, pâ¯=â¯0.005; CRUSADE 41⯱â¯19 vs 28⯱â¯17, pâ¯<â¯0.001). There were no significant differences in time to coronary angiography and revascularization rates between sex groups. A lower proportion of women received high-potency antiplatelet agents (29% vs 41.3%, pâ¯=â¯0.004). In-hospital evolution and one-year mortality were similar between groups.CONCLUSIONS:
In our population, there were no gender differences in management and prognosis of ACS. Differences in risk profile among groups could have an influence on antiplatelet therapy.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Platelet Aggregation Inhibitors
/
Acute Coronary Syndrome
/
Healthcare Disparities
/
Myocardial Revascularization
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Determinantes_sociais_saude
/
Equity_inequality
/
Patient_preference
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Cardiovasc Revasc Med
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
Year:
2019
Document type:
Article