Clinical Significance of Isolates Known to Be Blood Culture Contaminants in Pediatric Patients.
Medicina (Kaunas)
; 55(10)2019 Oct 17.
Article
in En
| MEDLINE
| ID: mdl-31627324
ABSTRACT
Background and objectives:
The objective of this study was to investigate the clinical significance of isolates from blood stream infection known to be blood culture contaminants in pediatric patients. Materials andMethods:
Microbiological reports and medical records of all blood culture tests issued from 2002 to 2012 (n = 76,331) were retrospectively reviewed. Evaluation for potential contaminants were done by reviewing medical records of patients with the following isolates coagulase-negative Staphylococcus, viridans group Streptococcus, Bacillus, Corynebacterium, Micrococcus, Aerococcus, and Proprionibacterium species. Repeated cultures with same isolates were considered as a single case. Cases were evaluated for their status as a pathogen.Results:
Coagulase-negative Staphylococcus had clinical significance in 23.8% of all cases. Its rate of being a true pathogen was particularly high in patients with malignancy (43.7%). Viridans group Streptococcus showed clinical significance in 46.2% of all cases. Its rate of being a true pathogen was similar regardless of the underlying morbidity of the patient. The rate of being a true pathogens for remaining isolates was 27.7% for Bacillus and 19.0% for Corynebacterium species.Conclusions:
Coagulase-negative Staphylococcus and viridans group Streptococcus isolates showed high probability of being true pathogens in the pediatric population, especially in patients with underlying malignancy.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pediatrics
/
Bacteremia
/
Blood Culture
Type of study:
Observational_studies
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Language:
En
Journal:
Medicina (Kaunas)
Journal subject:
MEDICINA
Year:
2019
Document type:
Article