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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Ross, Nathan T; Lohmann, Felix; Carbonneau, Seth; Fazal, Aleem; Weihofen, Wilhelm A; Gleim, Scott; Salcius, Michael; Sigoillot, Frederic; Henault, Martin; Carl, Sarah H; Rodríguez-Molina, Juan B; Miller, Howard R; Brittain, Scott M; Murphy, Jason; Zambrowski, Mark; Boynton, Geoffrey; Wang, Yuan; Chen, Aye; Molind, Gregory J; Wilbertz, Johannes H; Artus-Revel, Caroline G; Jia, Min; Akinjiyan, Favour A; Turner, Jonathan; Knehr, Judith; Carbone, Walter; Schuierer, Sven; Reece-Hoyes, John S; Xie, Kevin; Saran, Chitra; Williams, Eric T; Roma, Guglielmo; Spencer, Matt; Jenkins, Jeremy; George, Elizabeth L; Thomas, Jason R; Michaud, Gregory; Schirle, Markus; Tallarico, John; Passmore, Lori A; Chao, Jeffrey A; Beckwith, Rohan E J.
Affiliation
  • Ross NT; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Lohmann F; Vertex Pharmaceuticals, Boston, MA, USA.
  • Carbonneau S; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Fazal A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Weihofen WA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Gleim S; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Salcius M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Sigoillot F; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Henault M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Carl SH; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Rodríguez-Molina JB; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Miller HR; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Brittain SM; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Murphy J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Zambrowski M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Boynton G; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Wang Y; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Chen A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Molind GJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Wilbertz JH; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Artus-Revel CG; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Jia M; University of Basel, Basel, Switzerland.
  • Akinjiyan FA; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Turner J; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Knehr J; University of Basel, Basel, Switzerland.
  • Carbone W; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Schuierer S; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Reece-Hoyes JS; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Xie K; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Saran C; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Williams ET; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Roma G; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Spencer M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Jenkins J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • George EL; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Thomas JR; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Michaud G; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Schirle M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Tallarico J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Passmore LA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Chao JA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Beckwith REJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
Nat Chem Biol ; 16(1): 50-59, 2020 01.
Article in En | MEDLINE | ID: mdl-31819276

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / RNA Precursors / Leukemia, Myeloid, Acute / Cleavage And Polyadenylation Specificity Factor Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / RNA Precursors / Leukemia, Myeloid, Acute / Cleavage And Polyadenylation Specificity Factor Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication: