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Evaluation of the anti-cervical cancer effect of a prodrug ：CBZ-AAN-DOX with hypoxic cell culture and tumor-bearing zebrafish models.
Chen, Hong-Ce; Rui, Wen; You, Si-Yuan; Liu, Xia-Wan; Huang, Jun; Chen, Hong-Yuan.
Affiliation
  • Chen HC; Department of Pathogenic Biology and Immunology, School of Life Sciences and Biopharmaceuticals, Guangdong Pharmaceutical University, Guangzhou, 510632, Guangdong Province, PR China.
  • Rui W; Centre for Novel Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong Province, PR China; Guangdong Engineering & Technology Research Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong Prov
  • You SY; Department of Pathogenic Biology and Immunology, School of Life Sciences and Biopharmaceuticals, Guangdong Pharmaceutical University, Guangzhou, 510632, Guangdong Province, PR China.
  • Liu XW; Department of Pathogenic Biology and Immunology, School of Life Sciences and Biopharmaceuticals, Guangdong Pharmaceutical University, Guangzhou, 510632, Guangdong Province, PR China.
  • Huang J; Key Laboratory of Immunology, Sino-French Hoffmann Institute, School of Basic Medical Sciences; Guangdong Provincial Key Laboratory of Allergy & Clinical Immunology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong Province, PR China.
  • Chen HY; Department of Pathogenic Biology and Immunology, School of Life Sciences and Biopharmaceuticals, Guangdong Pharmaceutical University, Guangzhou, 510632, Guangdong Province, PR China; Guangdong Engineering & Technology Research Center of Topical Precise Drug Delivery System, Guangdong Pharmaceuti
Exp Cell Res ; 391(1): 111980, 2020 06 01.
Article in En | MEDLINE | ID: mdl-32229193
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Cysteine Endopeptidases / Prodrugs / Doxorubicin / Gene Expression Regulation, Neoplastic / Uterine Cervical Neoplasms / Antibiotics, Antineoplastic / Neovascularization, Pathologic Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Exp Cell Res Year: 2020 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Cysteine Endopeptidases / Prodrugs / Doxorubicin / Gene Expression Regulation, Neoplastic / Uterine Cervical Neoplasms / Antibiotics, Antineoplastic / Neovascularization, Pathologic Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Exp Cell Res Year: 2020 Document type: Article Country of publication: