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Insights into the Role of Innate Immunity in Cervicovaginal Papillomavirus Infection from Studies Using Gene-Deficient Mice.
Scagnolari, Carolina; Cannella, Fabiana; Pierangeli, Alessandra; Mellinger Pilgrim, Rebecca; Antonelli, Guido; Rowley, Dayana; Wong, Margaret; Best, Simon; Xing, Deyin; Roden, Richard B S; Viscidi, Raphael.
Affiliation
  • Scagnolari C; Laboratory of Virology, Department of Molecular Medicine, Sapienza University, Rome, Italy carolina.scagnolari@uniroma1.it rviscid1@jhmi.edu.
  • Cannella F; Institute Pasteur-Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.
  • Pierangeli A; Laboratory of Virology, Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Mellinger Pilgrim R; Institute Pasteur-Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.
  • Antonelli G; Laboratory of Virology, Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Rowley D; Institute Pasteur-Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.
  • Wong M; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Best S; Laboratory of Virology, Department of Molecular Medicine, Sapienza University, Rome, Italy.
  • Xing D; Institute Pasteur-Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.
  • Roden RBS; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Viscidi R; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Virol ; 94(12)2020 06 01.
Article in En | MEDLINE | ID: mdl-32295905
Subject(s)
Host-Pathogen Interactions/immunology; Myeloid Differentiation Factor 88/immunology; Papillomaviridae/immunology; Papillomavirus Infections/immunology; RNA, Messenger/immunology; RNA, Viral/immunology; Receptors, Interleukin-1 Type I/immunology; Adaptor Proteins, Signal Transducing/deficiency; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/immunology; Alternative Splicing; Animals; Caspase 1/deficiency; Caspase 1/genetics; Caspase 1/immunology; Cervix Uteri/immunology; Cervix Uteri/virology; Female; Gene Expression Regulation; Host-Pathogen Interactions/genetics; Humans; Immunity, Innate; Membrane Proteins/deficiency; Membrane Proteins/genetics; Membrane Proteins/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88/deficiency; Myeloid Differentiation Factor 88/genetics; Papillomaviridae/growth & development; Papillomaviridae/metabolism; Papillomavirus Infections/genetics; Papillomavirus Infections/virology; RNA, Messenger/genetics; RNA, Viral/genetics; Receptor-Interacting Protein Serine-Threonine Kinase 2/deficiency; Receptor-Interacting Protein Serine-Threonine Kinase 2/genetics; Receptor-Interacting Protein Serine-Threonine Kinase 2/immunology; Receptors, CCR6/deficiency; Receptors, CCR6/genetics; Receptors, CCR6/immunology; Receptors, CXCR3/deficiency; Receptors, CXCR3/genetics; Receptors, CXCR3/immunology; Receptors, Interleukin-1 Type I/deficiency; Receptors, Interleukin-1 Type I/genetics; Receptors, Interleukin-8B/deficiency; Receptors, Interleukin-8B/genetics; Receptors, Interleukin-8B/immunology; STAT1 Transcription Factor/deficiency; STAT1 Transcription Factor/genetics; STAT1 Transcription Factor/immunology; Signal Transduction; Vagina/immunology; Vagina/virology
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papillomaviridae / RNA, Messenger / RNA, Viral / Papillomavirus Infections / Myeloid Differentiation Factor 88 / Receptors, Interleukin-1 Type I / Host-Pathogen Interactions Type of study: Prognostic_studies Language: En Journal: J Virol Year: 2020 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papillomaviridae / RNA, Messenger / RNA, Viral / Papillomavirus Infections / Myeloid Differentiation Factor 88 / Receptors, Interleukin-1 Type I / Host-Pathogen Interactions Type of study: Prognostic_studies Language: En Journal: J Virol Year: 2020 Document type: Article Country of publication: