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Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aß42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models.
Rong, Zhouyi; Cheng, Baoying; Zhong, Li; Ye, Xiaowen; Li, Xin; Jia, Lin; Li, Yanfang; Shue, Francis; Wang, Na; Cheng, Yiyun; Huang, Xiaohua; Liu, Chia-Chen; Fryer, John D; Wang, Xin; Zhang, Yun-Wu; Zheng, Honghua.
Affiliation
  • Rong Z; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Cheng B; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Zhong L; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Ye X; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Li X; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Jia L; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Li Y; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Shue F; Shenzhen Research Institute, Xiamen University, Shenzhen, China.
  • Wang N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Cheng Y; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Huang X; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Liu CC; Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, China.
  • Fryer JD; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Wang X; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Zhang YW; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China.
  • Zheng H; State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, China.
FASEB J ; 34(8): 10984-10997, 2020 08.
Article in En | MEDLINE | ID: mdl-32613609
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Neuropeptides / Cell Movement / Amyloid beta-Peptides / Microglia / Cdc42 GTP-Binding Protein / Rac1 GTP-Binding Protein / Myeloid Cells / Focal Adhesion Kinase 1 / GTP Phosphohydrolases Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Neuropeptides / Cell Movement / Amyloid beta-Peptides / Microglia / Cdc42 GTP-Binding Protein / Rac1 GTP-Binding Protein / Myeloid Cells / Focal Adhesion Kinase 1 / GTP Phosphohydrolases Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication: