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Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models.
Yamada, Makiko; Ishizuka, Tomoko; Inoue, Shin-Ichi; Rozehnal, Veronika; Fischer, Thomas; Sugiyama, Daisuke.
Affiliation
  • Yamada M; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.) yamada.makiko.jr@daiichisankyo.co.jp.
  • Ishizuka T; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Inoue SI; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Rozehnal V; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Fischer T; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
  • Sugiyama D; Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.Y., T.I., S.I., D.S.) and Tissue and Cell Research Center Munich, Daiichi Sankyo Europe GmbH, Martinsried, Germany (V.R., T.F.).
Drug Metab Dispos ; 48(9): 769-777, 2020 09.
Article in En | MEDLINE | ID: mdl-32616542
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Sulfones / Mineralocorticoid Receptor Antagonists / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Inhibitors / Models, Biological Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Male Country/Region as subject: Asia Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Sulfones / Mineralocorticoid Receptor Antagonists / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Inhibitors / Models, Biological Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans / Male Country/Region as subject: Asia Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Country of publication: