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Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease.
Lazewska, Dorota; Bajda, Marek; Kaleta, Maria; Zareba, Paula; Doroz-Plonka, Agata; Siwek, Agata; Alachkar, Alaa; Mogilski, Szczepan; Saad, Ali; Kuder, Kamil; Olejarz-Maciej, Agnieszka; Godyn, Justyna; Stary, Dorota; Sudol, Sylwia; Wiecek, Malgorzata; Latacz, Gniewomir; Walczak, Maria; Handzlik, Jadwiga; Sadek, Bassem; Malawska, Barbara; Kiec-Kononowicz, Katarzyna.
Affiliation
  • Lazewska D; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl.
  • Bajda M; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Kaleta M; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Zareba P; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Doroz-Plonka A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Alachkar A; Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 1766, Al Ain, United Arab Emirates.
  • Mogilski S; Department of Pharmacodynamic, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Saad A; Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 1766, Al Ain, United Arab Emirates.
  • Kuder K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Olejarz-Maciej A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Godyn J; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Stary D; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Sudol S; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Wiecek M; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Walczak M; Department of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna Str 9, 30-688, Kraków, Poland.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Sadek B; Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 1766, Al Ain, United Arab Emirates.
  • Malawska B; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
  • Kiec-Kononowicz K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna Str. 9, 30-688, Kraków, Poland.
Eur J Med Chem ; 207: 112743, 2020 Dec 01.
Article in En | MEDLINE | ID: mdl-32882609

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Receptors, Histamine H3 / Molecular Targeted Therapy / Alzheimer Disease Limits: Animals / Humans / Male Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Receptors, Histamine H3 / Molecular Targeted Therapy / Alzheimer Disease Limits: Animals / Humans / Male Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication: