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Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model.
Yamanashi, Takehiko; Iwata, Masaaki; Shibushita, Midori; Tsunetomi, Kyohei; Nagata, Mayu; Kajitani, Naofumi; Miura, Akihiko; Matsuo, Ryoichi; Nishiguchi, Tsuyoshi; Kato, Takahiro A; Setoyama, Daiki; Shirayama, Yukihiko; Watanabe, Ken; Shinozaki, Gen; Kaneko, Koichi.
Affiliation
  • Yamanashi T; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Iwata M; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Shibushita M; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan. yanmasa@f8.dion.ne.jp.
  • Tsunetomi K; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Nagata M; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Kajitani N; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Miura A; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Matsuo R; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Nishiguchi T; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Kato TA; Department of Neuropsychiatry, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago, Tottori, 683-8503, Japan.
  • Setoyama D; Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Shirayama Y; Clinical Laboratories, Kyushu University Hospital, Fukuoka, Japan.
  • Watanabe K; Department of Psychiatry, Teikyo University Chiba Medical Center, Ichihara, Japan.
  • Shinozaki G; Watanabe Hospital, Tottori, Japan.
  • Kaneko K; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Sci Rep ; 10(1): 21629, 2020 12 10.
Article in En | MEDLINE | ID: mdl-33303808
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Stress Disorders, Post-Traumatic / 3-Hydroxybutyric Acid / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Stress Disorders, Post-Traumatic / 3-Hydroxybutyric Acid / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Country of publication: