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Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension.
McCray, Brett A; Diehl, Erika; Sullivan, Jeremy M; Aisenberg, William H; Zaccor, Nicholas W; Lau, Alexander R; Rich, Dominick J; Goretzki, Benedikt; Hellmich, Ute A; Lloyd, Thomas E; Sumner, Charlotte J.
Affiliation
  • McCray BA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. bmccray3@jhmi.edu.
  • Diehl E; Department of Chemistry, Biochemistry Section, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
  • Sullivan JM; Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-Universität, Frankfurt am Main, Germany.
  • Aisenberg WH; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Zaccor NW; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Lau AR; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Rich DJ; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Goretzki B; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Hellmich UA; Department of Chemistry, Biochemistry Section, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
  • Lloyd TE; Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-Universität, Frankfurt am Main, Germany.
  • Sumner CJ; Department of Chemistry, Biochemistry Section, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
Nat Commun ; 12(1): 1444, 2021 03 04.
Article in En | MEDLINE | ID: mdl-33664271
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurites / Peripheral Nervous System Diseases / RhoA GTP-Binding Protein / TRPV Cation Channels Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurites / Peripheral Nervous System Diseases / RhoA GTP-Binding Protein / TRPV Cation Channels Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Country of publication: