Evaluation of the consistency ratios of cervical smear, cervical biopsy and conization results.
Ginekol Pol
; 92(11): 778-783, 2021.
Article
in En
| MEDLINE
| ID: mdl-33914320
ABSTRACT
OBJECTIVES:
Possible discrepancies between the cervical smear, biopsy histology and loop electrosurgical excision procedure (LEEP) results of the same patient is a matter of debate in the literature. In this study, we investigate the degree to which these results differ, and the clinical reasons for these differences. MATERIAL ANDMETHODS:
With a retrospective design, cervical smear, cervical biopsy and LEEP results of patients were compared in terms of consistency. One hundred sixty-four patients who underwent till LEEP procedure due to pathologic initial smear and biopsy results between January 2015 and March 2020 were included in the study.RESULTS:
Exact diagnosis discrepancy and high grade squamous intraepithelial lesion (HSIL) discrepancy were 78.9% and 50.0% between smear and cervical biopsy, 64.6% and 31.7% between cervical smear and LEEP and 43.8% and 28.1% between cervical biopsy and LEEP results, respectively. Age did not affect the consistency rates of pathologic results between smear-biopsy (p = 0.408) and biopsy-LEEP (p = 0.590). However, the probability of the consistency of smear and LEEP results exhibited a statistically significant linear relation with age (OR = 1.043, p = 0.015). HPV infections did not affect the discrepancy between smear-biopsy (p = 0.533), smear-LEEP (p = 1.000) and biopsy-LEEP (p = 0.529).CONCLUSIONS:
Smear technique has a serious discrepancy and under-diagnosis problem when its results are compared with biopsy and LEEP. The consistency between smear and LEEP results appears to improve with age. When HSIL is evaluated in terms of detection, this discrepancy decreases. A smear test can detect HSIL and carcinoma with a higher accuracy than low-grade lesions.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vaginal Smears
/
Biopsy
/
Uterine Cervical Neoplasms
/
Conization
Type of study:
Diagnostic_studies
/
Observational_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Ginekol Pol
Year:
2021
Document type:
Article
Affiliation country: