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Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo- and radiation therapies.
Qi, Lin; Lindsay, Holly; Kogiso, Mari; Du, Yuchen; Braun, Frank K; Zhang, Huiyuan; Guo, Lei; Zhao, Sibo; Injac, Sarah G; Baxter, Patricia A; Su, Jack Mf; Xiao, Sophie; Erickson, Stephen W; Earley, Eric J; Teicher, Beverly; Smith, Malcolm A; Li, Xiao-Nan.
Affiliation
  • Qi L; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Lindsay H; Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Kogiso M; Department of Pharmacology, School of Medicine, Sun Yat-Sen University, Shenzhen, 518107, China.
  • Du Y; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Braun FK; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Zhang H; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Guo L; Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Zhao S; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Injac SG; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Baxter PA; Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, USA.
  • Su JM; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Xiao S; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Erickson SW; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Earley EJ; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
  • Teicher B; Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Smith MA; RTI International, Research Triangle Park, NC, USA.
  • Li XN; RTI International, Research Triangle Park, NC, USA.
Lab Invest ; 102(2): 185-193, 2022 02.
Article in En | MEDLINE | ID: mdl-34802040
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Xenograft Model Antitumor Assays / Enzyme Inhibitors / Enhancer of Zeste Homolog 2 Protein Limits: Adolescent / Animals / Child / Female / Humans / Infant / Male Language: En Journal: Lab Invest Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Xenograft Model Antitumor Assays / Enzyme Inhibitors / Enhancer of Zeste Homolog 2 Protein Limits: Adolescent / Animals / Child / Female / Humans / Infant / Male Language: En Journal: Lab Invest Year: 2022 Document type: Article Affiliation country: Country of publication: