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Protein S-Leu17Pro disrupts the hydrophobicity of its signal peptide causing a proteasome-dependent degradation.
Okada, Kentaro; Tamura, Shogo; Suzuki, Nobuaki; Odaira, Koya; Mukaide, Masato; Fujii, Wataru; Katsuragi, Yumi; Suzuki, Atsuo; Kanematsu, Takeshi; Okamoto, Shuichi; Suzuki, Naruko; Katsumi, Akira; Matsushita, Tadashi; Kojima, Tetsuhito; Hayakawa, Fumihiko.
Affiliation
  • Okada K; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Tamura S; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: stamura@met.nagoya-u.ac.jp.
  • Suzuki N; Department of Transfusion Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Odaira K; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Mukaide M; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Fujii W; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Katsuragi Y; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Suzuki A; Department of Medical Technique, Nagoya University Hospital, Nagoya, Japan.
  • Kanematsu T; Department of Clinical Laboratory, Nagoya University Hospital, Nagoya, Japan.
  • Okamoto S; Department of Clinical Laboratory, Nagoya University Hospital, Nagoya, Japan.
  • Suzuki N; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Katsumi A; Department of Hematology, National Center for Geriatrics and Gerontology, Obu City, Japan.
  • Matsushita T; Department of Transfusion Medicine, Nagoya University Hospital, Nagoya, Japan; Department of Clinical Laboratory, Nagoya University Hospital, Nagoya, Japan.
  • Kojima T; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan; Aichi Health Promotion Foundation, Nagoya, Japan.
  • Hayakawa F; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Thromb Res ; 210: 26-32, 2022 Feb.
Article in En | MEDLINE | ID: mdl-34968852
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein S / Proteasome Endopeptidase Complex Limits: Animals / Humans Language: En Journal: Thromb Res Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein S / Proteasome Endopeptidase Complex Limits: Animals / Humans Language: En Journal: Thromb Res Year: 2022 Document type: Article Affiliation country: Country of publication: