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The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation.
Kleiber, Nicole; Lemus-Diaz, Nicolas; Stiller, Carina; Heinrichs, Marleen; Mai, Mandy Mong-Quyen; Hackert, Philipp; Richter-Dennerlein, Ricarda; Höbartner, Claudia; Bohnsack, Katherine E; Bohnsack, Markus T.
Affiliation
  • Kleiber N; Department of Molecular Biology, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Lemus-Diaz N; Department of Molecular Biology, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Stiller C; Institute of Organic Chemistry, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Heinrichs M; Department of Cellular Biochemistry, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Mai MM; Department of Cellular Biochemistry, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Hackert P; Department of Molecular Biology, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Richter-Dennerlein R; Department of Cellular Biochemistry, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Höbartner C; Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), Göttingen, Germany.
  • Bohnsack KE; Institute of Organic Chemistry, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Bohnsack MT; Department of Molecular Biology, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany. katherine.bohnsack@med.uni-goettingen.de.
Nat Commun ; 13(1): 209, 2022 01 11.
Article in En | MEDLINE | ID: mdl-35017528
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anticodon / RNA, Transfer, Ser / RNA, Transfer, Thr / RNA, Mitochondrial / Methyltransferases / Mitochondria Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anticodon / RNA, Transfer, Ser / RNA, Transfer, Thr / RNA, Mitochondrial / Methyltransferases / Mitochondria Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication: