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Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.
Box, Helen; Pennington, Shaun H; Kijak, Edyta; Tatham, Lee; Caygill, Claire H; Lopeman, Rose C; Jeffreys, Laura N; Herriott, Joanne; Sharp, Joanne; Neary, Megan; Valentijn, Anthony; Pertinez, Henry; Curley, Paul; Arshad, Usman; Rajoli, Rajith Kr; Rannard, Steve; Stewart, James P; Biagini, Giancarlo A; Owen, Andrew.
Affiliation
  • Box H; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Pennington SH; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Kijak E; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA.
  • Tatham L; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Caygill CH; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Lopeman RC; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Jeffreys LN; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Herriott J; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA.
  • Sharp J; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA.
  • Neary M; Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA.
  • Valentijn A; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Pertinez H; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Curley P; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Arshad U; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Rajoli RK; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Rannard S; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Stewart JP; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
  • Biagini GA; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, L7 3NY, UK.
  • Owen A; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L7 3NY, UK.
bioRxiv ; 2022 Mar 03.
Article in En | MEDLINE | ID: mdl-35262084
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Full text: 1 Collection: 01-internacional Database: MEDLINE Aspects: Ethics Language: En Journal: BioRxiv Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Aspects: Ethics Language: En Journal: BioRxiv Year: 2022 Document type: Article Affiliation country: Country of publication: