Your browser doesn't support javascript.
loading
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls.
Simkin, Dina; Papakis, Vasileios; Bustos, Bernabe I; Ambrosi, Christina M; Ryan, Steven J; Baru, Valeriya; Williams, Luis A; Dempsey, Graham T; McManus, Owen B; Landers, John E; Lubbe, Steven J; George, Alfred L; Kiskinis, Evangelos.
Affiliation
  • Simkin D; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Papakis V; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Bustos BI; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Simpson Querrey Center of Neurogenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Ambrosi CM; Q-State Biosciences, Cambridge, MA 02139, USA.
  • Ryan SJ; Q-State Biosciences, Cambridge, MA 02139, USA.
  • Baru V; Q-State Biosciences, Cambridge, MA 02139, USA.
  • Williams LA; Q-State Biosciences, Cambridge, MA 02139, USA.
  • Dempsey GT; Q-State Biosciences, Cambridge, MA 02139, USA.
  • McManus OB; Q-State Biosciences, Cambridge, MA 02139, USA.
  • Landers JE; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Lubbe SJ; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Simpson Querrey Center of Neurogenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • George AL; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Kiskinis E; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60
Stem Cell Reports ; 17(4): 993-1008, 2022 04 12.
Article in En | MEDLINE | ID: mdl-35276091
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Stem Cell Reports Year: 2022 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Stem Cell Reports Year: 2022 Document type: Article Affiliation country: