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A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.
Liang, Rui; Tomita, Daisuke; Sasaki, Yusuke; Ginn, John; Michino, Mayako; Huggins, David J; Baxt, Leigh; Kargman, Stacia; Shahid, Maaz; Aso, Kazuyoshi; Duggan, Mark; Stamford, Andrew W; DeStanchina, Elisa; Liverton, Nigel; Meinke, Peter T; Foley, Michael A; Phillips, Richard E.
Affiliation
  • Liang R; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Tomita D; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Sasaki Y; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Ginn J; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Michino M; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Huggins DJ; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Baxt L; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10021, United States.
  • Kargman S; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Shahid M; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Aso K; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • Duggan M; Epigenetics Program, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, United States.
  • Stamford AW; Abramson Cancer Center, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, United States.
  • DeStanchina E; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Liverton N; LifeSci Consulting, LLC., 18243 SE Ridgeview Drive, Tequesta, Florida 33469, United States.
  • Meinke PT; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
  • Foley MA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Phillips RE; Tri-Institutional Therapeutics Discovery Institute, 413 East 69th Street, New York, New York 10021, United States.
ACS Med Chem Lett ; 13(3): 377-387, 2022 Mar 10.
Article in En | MEDLINE | ID: mdl-35300079
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2022 Document type: Article Affiliation country: Country of publication: