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USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
Nelson, Jessica K; Thin, May Zaw; Evan, Theodore; Howell, Steven; Wu, Mary; Almeida, Bruna; Legrave, Nathalie; Koenis, Duco S; Koifman, Gabriela; Sugimoto, Yoichiro; Llorian Sopena, Miriam; MacRae, James; Nye, Emma; Howell, Michael; Snijders, Ambrosius P; Prachalias, Andreas; Zen, Yoh; Sarker, Debashis; Behrens, Axel.
Affiliation
  • Nelson JK; Adult Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Thin MZ; Cancer Stem Cell Laboratory, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
  • Evan T; Adult Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Howell S; Cancer Stem Cell Laboratory, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
  • Wu M; Adult Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Almeida B; Proteomics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Legrave N; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Koenis DS; Experimental Histopathology, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Koifman G; Metabolomics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Sugimoto Y; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
  • Llorian Sopena M; Adult Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • MacRae J; Cancer Stem Cell Laboratory, The Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
  • Nye E; Hypoxia Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Howell M; Bioinformatics and Biostatistics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Snijders AP; Metabolomics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Prachalias A; Experimental Histopathology, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Zen Y; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Sarker D; Proteomics, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Behrens A; Hepatobiliary and Pancreatic Surgery, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.
Nat Commun ; 13(1): 2070, 2022 04 19.
Article in En | MEDLINE | ID: mdl-35440539

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication: