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Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.
Revie, Nicole M; Iyer, Kali R; Maxson, Michelle E; Zhang, Jiabao; Yan, Su; Fernandes, Caroline M; Meyer, Kirsten J; Chen, Xuefei; Skulska, Iwona; Fogal, Meea; Sanchez, Hiram; Hossain, Saif; Li, Sheena; Yashiroda, Yoko; Hirano, Hiroyuki; Yoshida, Minoru; Osada, Hiroyuki; Boone, Charles; Shapiro, Rebecca S; Andes, David R; Wright, Gerard D; Nodwell, Justin R; Del Poeta, Maurizio; Burke, Martin D; Whitesell, Luke; Robbins, Nicole; Cowen, Leah E.
Affiliation
  • Revie NM; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Iyer KR; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Maxson ME; Program in Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.
  • Zhang J; Department of Chemistry, Roger Adams Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
  • Yan S; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
  • Fernandes CM; Department of Chemistry, Roger Adams Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
  • Meyer KJ; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
  • Chen X; Department of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, USA.
  • Skulska I; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
  • Fogal M; David Braley Centre for Antibiotics Discovery, M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, L8S 4K1, Canada.
  • Sanchez H; Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
  • Hossain S; Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
  • Li S; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
  • Yashiroda Y; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI, USA.
  • Hirano H; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Yoshida M; Department of Molecular Genetics, Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada.
  • Osada H; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Boone C; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Shapiro RS; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Andes DR; Department of Biotechnology, Graduate School of Agricultural Life Sciences, The University of Tokyo, Tokyo, Japan.
  • Wright GD; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo, Japan.
  • Nodwell JR; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Del Poeta M; Department of Molecular Genetics, Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada.
  • Burke MD; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Whitesell L; Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
  • Robbins N; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
  • Cowen LE; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI, USA.
Nat Commun ; 13(1): 3634, 2022 06 25.
Article in En | MEDLINE | ID: mdl-35752611
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azoles / Fluconazole Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azoles / Fluconazole Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Country of publication: