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N1-methyl-pseudouridine is incorporated with higher fidelity than pseudouridine in synthetic RNAs.
Chen, Tien-Hao; Potapov, Vladimir; Dai, Nan; Ong, Jennifer L; Roy, Bijoyita.
Affiliation
  • Chen TH; RNA and Genome Editing, New England Biolabs Inc., Beverly, MA, 01915, USA.
  • Potapov V; RNA and Genome Editing, New England Biolabs Inc., Beverly, MA, 01915, USA.
  • Dai N; RNA and Genome Editing, New England Biolabs Inc., Beverly, MA, 01915, USA.
  • Ong JL; RNA and Genome Editing, New England Biolabs Inc., Beverly, MA, 01915, USA.
  • Roy B; RNA and Genome Editing, New England Biolabs Inc., Beverly, MA, 01915, USA. broy@neb.com.
Sci Rep ; 12(1): 13017, 2022 07 29.
Article in En | MEDLINE | ID: mdl-35906281
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudouridine / Nucleotides Type of study: Guideline Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudouridine / Nucleotides Type of study: Guideline Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: