Defining migraine days, based on longitudinal E-diary data.
Cephalalgia
; 43(5): 3331024231166625, 2023 05.
Article
in En
| MEDLINE
| ID: mdl-37021643
ABSTRACT
BACKGROUND:
There is a need for standardization of the definition of a migraine day for clinical and research purposes.METHODS:
We prospectively compared different definitions of a migraine day with E-diary data of n = 1494 patients with migraine. We used a baseline definition based on migraine characteristics with a duration of ≥4 hours OR triptan intake (independently from its effect) OR (visual) aura lasting 5-60 minutes.RESULTS:
Of all migraine days defined by triptan intake only, 66.2% had a duration <4 hours. Adjusting the headache duration criterion to ≥30 minutes led to a decrease in days defined by triptan intake only and resulted in a 5.4% increase in total migraine days (equals 0.45 migraine day increase in monthly migraine days). These additional migraine days had a median duration of 2.5 hours.CONCLUSION:
We propose to define a migraine day as follows 1) (a) headache duration ≥30 minutes; (b) matching ≥2 of four characteristics unilateral, pulsating, moderate to severe pain, aggravation by or causing avoidance of routine physical activity; and (c) during headache ≥1 of the following nausea and/or vomiting, photophobia and phonophobia or 2) (visual) aura duration 5-60 minutes or 3) a day with headache for which acute migraine-specific medication is used irrespective of its effect.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Epilepsy
/
Migraine Disorders
Limits:
Humans
Language:
En
Journal:
Cephalalgia
Year:
2023
Document type:
Article
Affiliation country: