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Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex.
Kandhaya-Pillai, Renuka; Miro-Mur, Francesc; Alijotas-Reig, Jaume; Tchkonia, Tamar; Schwartz, Simo; Kirkland, James L; Oshima, Junko.
Affiliation
  • Kandhaya-Pillai R; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
  • Miro-Mur F; Systemic Autoimmune Diseases Research Unit, Vall d’Hebron Research Institute (VHIR), Barcelona 08035, Spain.
  • Alijotas-Reig J; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA.
  • Tchkonia T; Systemic Autoimmune Diseases Research Unit, Vall d’Hebron Research Institute (VHIR), Barcelona 08035, Spain.
  • Schwartz S; Systemic Autoimmune Diseases Research Unit, Vall d’Hebron Research Institute (VHIR), Barcelona 08035, Spain.
  • Kirkland JL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA.
  • Oshima J; Department of Physiology, Mayo Clinic, Rochester, MN 55905, USA.
Aging (Albany NY) ; 15(10): 4012-4034, 2023 05 22.
Article in En | MEDLINE | ID: mdl-37219418
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Tumor Necrosis Factor-alpha Type of study: Prognostic_studies Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Tumor Necrosis Factor-alpha Type of study: Prognostic_studies Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2023 Document type: Article Affiliation country: Country of publication: