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A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.
Moretton, Amandine; Kourtis, Savvas; Gañez Zapater, Antoni; Calabrò, Chiara; Espinar Calvo, Maria Lorena; Fontaine, Frédéric; Darai, Evangelia; Abad Cortel, Etna; Block, Samuel; Pascual-Reguant, Laura; Pardo-Lorente, Natalia; Ghose, Ritobrata; Vander Heiden, Matthew G; Janic, Ana; Müller, André C; Loizou, Joanna I; Sdelci, Sara.
Affiliation
  • Moretton A; Center for Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
  • Kourtis S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Gañez Zapater A; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Calabrò C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Espinar Calvo ML; Center for Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
  • Fontaine F; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Darai E; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Abad Cortel E; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Block S; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
  • Pascual-Reguant L; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Pardo-Lorente N; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Ghose R; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Vander Heiden MG; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
  • Janic A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Müller AC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Loizou JI; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Sdelci S; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Mol Syst Biol ; 19(7): e11267, 2023 07 11.
Article in En | MEDLINE | ID: mdl-37259925
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspartic Acid / Peroxiredoxins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspartic Acid / Peroxiredoxins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: Country of publication: