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Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice.
Puente-Massaguer, Eduard; Vasilev, Kirill; Beyer, Annika; Loganathan, Madhumathi; Francis, Benjamin; Scherm, Michael J; Arunkumar, Guha Asthagiri; González-Domínguez, Irene; Zhu, Xueyong; Wilson, Ian A; Coughlan, Lynda; Sun, Weina; Palese, Peter; Krammer, Florian.
Affiliation
  • Puente-Massaguer E; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Vasilev K; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Beyer A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Loganathan M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Francis B; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Scherm MJ; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Arunkumar GA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • González-Domínguez I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Coughlan L; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Sun W; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Palese P; Center for Vaccine Development and Global Health (CVD), University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sci Adv ; 9(37): eadi4753, 2023 09 15.
Article in En | MEDLINE | ID: mdl-37703367
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Influenza Vaccines Limits: Animals Language: En Journal: Sci Adv Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Influenza Vaccines Limits: Animals Language: En Journal: Sci Adv Year: 2023 Document type: Article Affiliation country: Country of publication: