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Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann, Alexander; Ohlei, Olena; Küçükali, Fahri; Bos, Isabelle J; Timsina, Jigyasha; Vos, Stephanie; Prokopenko, Dmitry; Tijms, Betty M; Andreasson, Ulf; Blennow, Kaj; Vandenberghe, Rik; Scheltens, Philip; Teunissen, Charlotte E; Engelborghs, Sebastiaan; Frisoni, Giovanni B; Blin, Oliver; Richardson, Jill C; Bordet, Régis; Lleó, Alberto; Alcolea, Daniel; Popp, Julius; Marsh, Thomas W; Gorijala, Priyanka; Clark, Christopher; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Dobson, Richard J B; Legido-Quigley, Cristina; Van Broeckhoven, Christine; Tanzi, Rudolph E; Ten Kate, Mara; Lill, Christina M; Barkhof, Frederik; Cruchaga, Carlos; Lovestone, Simon; Streffer, Johannes; Zetterberg, Henrik; Visser, Pieter Jelle; Sleegers, Kristel; Bertram, Lars.
Affiliation
  • Neumann A; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • Ohlei O; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Küçükali F; Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, Netherlands.
  • Bos IJ; Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), University of Lübeck, Ratzeburger Allee 160, V50.2M, Lübeck, 23562, Germany.
  • Timsina J; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
  • Vos S; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Prokopenko D; Netherlands Institute for Health Services Research, Utrecht, Netherlands.
  • Tijms BM; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
  • Andreasson U; NeuroGenomics and Informatics Center, Washington University School of Medicine, St Louis, MO, USA.
  • Blennow K; Alzheimer Centrum Limburg, Maastricht University, Maastricht, Netherlands.
  • Vandenberghe R; Genetics and Aging Unit and McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
  • Scheltens P; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Teunissen CE; Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
  • Engelborghs S; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Frisoni GB; Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
  • Blin O; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Richardson JC; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium.
  • Bordet R; Neurology Service, University Hospital Leuven, Leuven, Belgium.
  • Lleó A; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Alcolea D; Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Popp J; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Marsh TW; Department of Neurology and Memory Clinic, Universitair Ziekenhuis Brussel (UZ Brussel) and Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
  • Gorijala P; Memory Center, Department of Rehabilitation and Geriatrics, Geneva University and University Hospitals, Geneva, Switzerland.
  • Clark C; Clinical Pharmacology & Pharmacovigilance Department, Marseille University Hospital, Marseille, France.
  • Peyratout G; Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Stevenage, UK.
  • Martinez-Lage P; Neuroscience & Cognition, CHU de Lille, University of Lille, Inserm, France.
  • Tainta M; Memory Unit, Neurology Department, Hospital de Sant Pau, Barcelona, Spain.
  • Dobson RJB; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Legido-Quigley C; Memory Unit, Neurology Department, Hospital de Sant Pau, Barcelona, Spain.
  • Van Broeckhoven C; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Tanzi RE; Department of Psychiatry, Psychotherapy and Psychosomatics, University of Zürich, Zurich, Switzerland.
  • Ten Kate M; Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland.
  • Lill CM; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
  • Barkhof F; NeuroGenomics and Informatics Center, Washington University School of Medicine, St Louis, MO, USA.
  • Cruchaga C; Division of Biology & Biomedical Sciences, Washington University in St. Louis, St Louis, MO, USA.
  • Lovestone S; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
  • Streffer J; NeuroGenomics and Informatics Center, Washington University School of Medicine, St Louis, MO, USA.
  • Zetterberg H; Department of Psychiatry, Psychotherapy and Psychosomatics, University of Zürich, Zurich, Switzerland.
  • Visser PJ; Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland.
  • Sleegers K; Center for Research and Advanced Therapies, CITA-Alzheimer Foundation, San Sebastian, Spain.
  • Bertram L; Center for Research and Advanced Therapies, CITA-Alzheimer Foundation, San Sebastian, Spain.
Genome Med ; 15(1): 79, 2023 10 04.
Article in En | MEDLINE | ID: mdl-37794492
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Genome Med Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Genome Med Year: 2023 Document type: Article Affiliation country: Country of publication: