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An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy.
Bakema, Jantine E; Stigter-van Walsum, Marijke; Harris, Jeffrey R; Ganzevles, Sonja H; Muthuswamy, Anantharaman; Houtkamp, Mischa; Plantinga, Theo S; Bloemena, Elisabeth; Brakenhoff, Ruud H; Breij, Esther C W; van de Ven, Rieneke.
Affiliation
  • Bakema JE; Department of Otolaryngology | Head & Neck Surgery, Amsterdam UMC, location VU University Medical Center, Amsterdam, The Netherlands.
  • Stigter-van Walsum M; Genmab, Utrecht, The Netherlands.
  • Harris JR; Department of Otolaryngology | Head & Neck Surgery, Amsterdam UMC, location VU University Medical Center, Amsterdam, The Netherlands.
  • Ganzevles SH; Cancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands.
  • Muthuswamy A; Genmab US Inc., Plainsboro, New Jersey.
  • Houtkamp M; Department of Otolaryngology | Head & Neck Surgery, Amsterdam UMC, location VU University Medical Center, Amsterdam, The Netherlands.
  • Plantinga TS; Cancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands.
  • Bloemena E; Amsterdam Institute for Infection and Immunity, Cancer Immunology, Amsterdam, The Netherlands.
  • Brakenhoff RH; Genmab US Inc., Plainsboro, New Jersey.
  • Breij ECW; Genmab, Utrecht, The Netherlands.
  • van de Ven R; Genmab, Utrecht, The Netherlands.
Mol Cancer Ther ; 23(2): 187-198, 2024 Feb 01.
Article in En | MEDLINE | ID: mdl-37828725
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Head and Neck Neoplasms Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Head and Neck Neoplasms Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2024 Document type: Article Affiliation country: Country of publication: