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Stochastic Interventional Vaccine Efficacy and Principal Surrogate Analyses of Antibody Markers as Correlates of Protection against Symptomatic COVID-19 in the COVE mRNA-1273 Trial.
Huang, Ying; Hejazi, Nima S; Blette, Bryan; Carpp, Lindsay N; Benkeser, David; Montefiori, David C; McDermott, Adrian B; Fong, Youyi; Janes, Holly E; Deng, Weiping; Zhou, Honghong; Houchens, Christopher R; Martins, Karen; Jayashankar, Lakshmi; Flach, Britta; Lin, Bob C; O'Connell, Sarah; McDanal, Charlene; Eaton, Amanda; Sarzotti-Kelsoe, Marcella; Lu, Yiwen; Yu, Chenchen; Kenny, Avi; Carone, Marco; Huynh, Chuong; Miller, Jacqueline; El Sahly, Hana M; Baden, Lindsey R; Jackson, Lisa A; Campbell, Thomas B; Clark, Jesse; Andrasik, Michele P; Kublin, James G; Corey, Lawrence; Neuzil, Kathleen M; Pajon, Rolando; Follmann, Dean; Donis, Ruben O; Koup, Richard A; Gilbert, Peter B.
Affiliation
  • Huang Y; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Hejazi NS; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Blette B; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
  • Carpp LN; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Benkeser D; Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.
  • Montefiori DC; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • McDermott AB; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Fong Y; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
  • Janes HE; Department of Surgery, Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Deng W; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Zhou H; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Houchens CR; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Martins K; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Jayashankar L; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Flach B; Moderna, Inc., Cambridge, MA 02139, USA.
  • Lin BC; Moderna, Inc., Cambridge, MA 02139, USA.
  • O'Connell S; Biomedical Advanced Research and Development Authority, Washington, DC 20201, USA.
  • McDanal C; Biomedical Advanced Research and Development Authority, Washington, DC 20201, USA.
  • Eaton A; Biomedical Advanced Research and Development Authority, Washington, DC 20201, USA.
  • Sarzotti-Kelsoe M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Lu Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Yu C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kenny A; Department of Surgery, Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Carone M; Department of Surgery, Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Huynh C; Department of Surgery, Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Miller J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • El Sahly HM; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Baden LR; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
  • Jackson LA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
  • Campbell TB; Biomedical Advanced Research and Development Authority, Washington, DC 20201, USA.
  • Clark J; Moderna, Inc., Cambridge, MA 02139, USA.
  • Andrasik MP; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Kublin JG; Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Corey L; Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, USA.
  • Neuzil KM; Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Pajon R; Department of Medicine, Division of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Follmann D; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Donis RO; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Koup RA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
  • Gilbert PB; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
  • On Behalf Of The Immune Assays; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Moderna Inc; Moderna, Inc., Cambridge, MA 02139, USA.
  • Coronavirus Vaccine Prevention Network CoVPN/Coronavirus Efficacy Cove; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • United States Government Usg/CoVPN Biostatistics Teams; Biomedical Advanced Research and Development Authority, Washington, DC 20201, USA.
Viruses ; 15(10)2023 09 29.
Article in En | MEDLINE | ID: mdl-37896806

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 / 2019-nCoV Vaccine mRNA-1273 Limits: Humans Language: En Journal: Viruses Year: 2023 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 / 2019-nCoV Vaccine mRNA-1273 Limits: Humans Language: En Journal: Viruses Year: 2023 Document type: Article Affiliation country: Country of publication: