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Significance of Organic Anion Transporter 2 and Organic Cation Transporter 2 in Creatinine Clearance: Mechanistic Evaluation Using Freshly Prepared Human Primary Renal Proximal Tubule Cells.
Mathialagan, Sumathy; Chung, Git; Pye, Keith; Rodrigues, A David; Varma, Manthena V S; Brown, Colin.
Affiliation
  • Mathialagan S; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.).
  • Chung G; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.).
  • Pye K; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.).
  • Rodrigues AD; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.).
  • Varma MVS; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.).
  • Brown C; Medicine Design, Pfizer Research and Development, Pfizer Inc., Groton, Connecticut (S.M., A.D.R., M.V.S.V.); and Newcells Biotech Limited, The Biosphere, Newcastle Upton Tyne, United Kingdom (G.C., K.P., C.B.) colin.brown@newcellsbiotech.co.uk.
J Pharmacol Exp Ther ; 388(1): 201-208, 2024 01 02.
Article in En | MEDLINE | ID: mdl-37977812
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organic Anion Transporters / Metformin Limits: Humans Language: En Journal: J Pharmacol Exp Ther Year: 2024 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organic Anion Transporters / Metformin Limits: Humans Language: En Journal: J Pharmacol Exp Ther Year: 2024 Document type: Article