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WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis.
Tai, Panpan; Chen, Xinyu; Jia, Guihua; Chen, Guanjun; Gong, Lian; Cheng, Yaxin; Li, Zhuan; Wang, Heng; Chen, Aiyan; Zhang, Ganghua; Zhu, Yuxing; Xiao, Mengqing; Wang, Zhanwang; Liu, Yunqing; Shan, Dongyong; He, Dong; Li, Moying; Zhan, Tianzuo; Khan, Abbas; Li, Xiaohui; Zeng, Xiangxiang; Li, Chaopeng; Ouyang, Dongsheng; Ai, Kelong; Chen, Xuan; Liu, Dongbo; Liu, Zhonghua; Wei, Dongqing; Cao, Ke.
Affiliation
  • Tai P; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Chen X; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Jia G; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
  • Chen G; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Gong L; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Cheng Y; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Li Z; The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University School of Medicine, Changsha, 410013, China.
  • Wang H; The Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Hunan Normal University School of Medicine, Changsha, 410013, China.
  • Chen A; Department of Pharmacy, Hunan Normal University School of Medicine, Changsha, 410013, China.
  • Zhang G; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
  • Zhu Y; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Xiao M; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Wang Z; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Liu Y; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Shan D; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • He D; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Li M; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Zhan T; Staff Hospital of Central South University, Central South University, Changsha, China.
  • Khan A; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Li X; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Zeng X; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
  • Li C; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
  • Ouyang D; College of Computer Science and Electronic Engineering, Hunan University, Changsha, China.
  • Ai K; Hunan Key Laboratory for Bioanalysis of Complex Matrix Samples, Changsha Duxact Biotech Co., Ltd, Changsha, China.
  • Chen X; Hunan Key Laboratory for Bioanalysis of Complex Matrix Samples, Changsha Duxact Biotech Co., Ltd, Changsha, China.
  • Liu D; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
  • Liu Z; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
  • Wei D; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
  • Cao K; College of Horticulture, Hunan Agricultural University, Changsha, China.
J Transl Med ; 21(1): 823, 2023 11 17.
Article in En | MEDLINE | ID: mdl-37978379
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotoxicity / Ferroptosis Limits: Animals Language: En Journal: J Transl Med Year: 2023 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotoxicity / Ferroptosis Limits: Animals Language: En Journal: J Transl Med Year: 2023 Document type: Article Affiliation country: Country of publication: