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CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells.
Vlassis, Arsenios; Jensen, Tanja L; Mohr, Marina; Jedrzejczyk, Dominika J; Meng, Xiangyou; Kovacs, Gergo; Morera-Gómez, Martí; Barghetti, Andrea; Muyo Abad, Sergi; Baumgartner, Roland F; Natarajan, Kedar N; Nielsen, Lars K; Warnecke, Tanya; Gill, Ryan T.
Affiliation
  • Vlassis A; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Jensen TL; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Mohr M; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Jedrzejczyk DJ; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Meng X; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Kovacs G; DTU Bioengineering, Technical University of Denmark, Søltofts Plads 224, 2800 Kongens Lyngby, Denmark.
  • Morera-Gómez M; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Barghetti A; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Muyo Abad S; Artisan Bio, 363 Centennial Parkway, Suite 310, Louisville, CO 80027, USA.
  • Baumgartner RF; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Natarajan KN; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
  • Nielsen LK; Artisan Bio, 363 Centennial Parkway, Suite 310, Louisville, CO 80027, USA.
  • Warnecke T; DTU Bioengineering, Technical University of Denmark, Søltofts Plads 224, 2800 Kongens Lyngby, Denmark.
  • Gill RT; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark.
iScience ; 26(12): 108287, 2023 Dec 15.
Article in En | MEDLINE | ID: mdl-38034357
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: IScience Year: 2023 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: IScience Year: 2023 Document type: Article Affiliation country: Country of publication: