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A naturally occurring G11S mutation in the 3C-like protease from the SARS-CoV-2 virus dramatically weakens the dimer interface.
Wang, Guanyu; Venegas, Felipe A; Rueda, Andres M; Weerasinghe, Nuwani W; Uggowitzer, Kevin A; Thibodeaux, Christopher J; Moitessier, Nicolas; Mittermaier, Anthony K.
Affiliation
  • Wang G; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Venegas FA; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Rueda AM; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Weerasinghe NW; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Uggowitzer KA; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Thibodeaux CJ; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Moitessier N; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
  • Mittermaier AK; Department of Chemistry, McGill University, Montreal, Quebec, Canada.
Protein Sci ; 33(1): e4857, 2024 Jan.
Article in En | MEDLINE | ID: mdl-38058248
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2024 Document type: Article Affiliation country: Country of publication: