Exploring the relationship between allergic contact dermatitis and atopic dermatitis in children: insights from a retrospective patch testing analysis.
Int J Dermatol
; 63(6): 795-798, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38219262
ABSTRACT
BACKGROUND:
Recent years have seen significant exploration into the potential link between allergic contact dermatitis and atopic dermatitis, yielding contradictory findings.METHODS:
A retrospective cohort analysis of children aged 2 to 18 who underwent patch testing at the pediatric dermatology clinic at a tertiary medical center in Israel was conducted.RESULTS:
Overall, 367 patients were included in the study, 31.6% of whom were diagnosed with atopic dermatitis. 160 children (43.6%) exhibited a positive reaction to at least one compound in the European baseline series. There was no statistically significant difference in reactivity between children with atopic dermatitis and those without (P = 0.848). Sub-analyses based on ethnicity, gender, and age did not reveal significant differences in overall European baseline series reactivity (P = 0.612, P = 0.446, P = 0.488, respectively). Sensitivity was notably higher when patch readings were conducted 72 h after application compared to 48 h [0.95 (CI 0.91-0.97) vs. 0.60 (CI 0.55-0.66)].CONCLUSIONS:
Patch testing is imperative for suspected cases of allergic contact dermatitis in all children, regardless of their atopic background. Further research is warranted to potentially replace the traditional 48-h reading with a single 72-h reading in future guidelines, contributing to enhanced efficiency and cost-effectiveness in clinical practice.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Patch Tests
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Dermatitis, Allergic Contact
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Dermatitis, Atopic
Type of study:
Guideline
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Observational_studies
Limits:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Country/Region as subject:
Asia
Language:
En
Journal:
Int J Dermatol
/
Int. j. dermatol
/
International journal of dermatology
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: