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Rebuilding the behavioral inhibition circuit to prevent opioid relapse.
Liu, Xiaoxing; Lu, Tangsheng; Han, Ying; Lu, Lin.
Affiliation
  • Liu X; Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China.
  • Lu T; National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence Research, Peking University, Beijing 100191, China; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
  • Han Y; National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence Research, Peking University, Beijing 100191, China.
  • Lu L; Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China; National Institute on Drug Dependence and Beijing
Neuron ; 112(5): 689-691, 2024 Mar 06.
Article in En | MEDLINE | ID: mdl-38452736
ABSTRACT
Failure in behavioral suppression is a key feature in substance use disorders, potentially leading to compulsive drug seeking and relapse. In this issue of Neuron, Paniccia et al.1 elucidated a heroin-damaged paraventricular nucleus of the thalamus (PVT)-accumbal circuit and how recovery of PVT function could prevent heroin relapse.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heroin / Analgesics, Opioid Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heroin / Analgesics, Opioid Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2024 Document type: Article Affiliation country: Country of publication: