Evaluation of inflammatory biomarkers affecting mortality in acute cholecystitis in the emergency department.
Bratisl Lek Listy
; 125(6): 365-370, 2024.
Article
in En
| MEDLINE
| ID: mdl-38757593
ABSTRACT
OBJECTIVES:
The aim of this study was to investigate the effectiveness of pan-immune inflammation value (PIV), systemic immune-inflammatory index (SII), and systemic inflammation response index (SIRI) in predicting mortality in acute cholecystitis (AC).BACKGROUND:
Abdominal pain is one of the most frequent complaints encountered by physicians at emergency department (ED).METHODS:
This clinical study is a cross-sectional study among patients admitted to the emergency department of a tertiary hospital and diagnosed with AC. Total survival curves were estimated by the KaplanâMeier method. Differences according to risk groups were determined by the log-rank test.RESULTS:
A total of 789 patients (survival 737, non-survival 52) diagnosed with AC were enrolled in the study. NLR and SII had an excellent diagnostic power in predicting 30-day mortality in the receiver operating characteristic (ROC) analysis, while the diagnostic power of SIRI and PIV was acceptable. It was observed that the probability of survival period decreased in the presence of NLR (>11.07), SII (>2315.18), SIRI (>6.55), and PIV (>1581.13) above the cut-off levels. The HRs of NLR, SII, SIRI, and PIV were 10.52, 7.44, 6.34, and 5.6, respectively.CONCLUSION:
NLR, SII, SIRI, and PIV may be useful markers in predicting 30-day mortality in patients with AC (Tab. 3, Fig. 5, Ref. 25).Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biomarkers
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Cholecystitis, Acute
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Emergency Service, Hospital
Limits:
Adult
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Aged
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Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
Bratisl Lek Listy
Year:
2024
Document type:
Article
Country of publication: