Your browser doesn't support javascript.
loading
Recalcitrant intussusception: exploring potential associations with Helicobacter pylori infection - a case report and literature review.
Wang, Kuan-Chieh; Chu, Chun-Hao; Chiang, Che-Ming; Zeng, Fu-Ruei; Huang, Ching-Wen; Lin, Chien-Ming.
Affiliation
  • Wang KC; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
  • Chu CH; Department of General Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Chiang CM; Department of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan.
  • Zeng FR; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec.2, Chenggong Rd., Neihu District, Taipei, 114, Taiwan.
  • Huang CW; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec.2, Chenggong Rd., Neihu District, Taipei, 114, Taiwan.
  • Lin CM; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec.2, Chenggong Rd., Neihu District, Taipei, 114, Taiwan.
Gut Pathog ; 16(1): 28, 2024 Jun 01.
Article in En | MEDLINE | ID: mdl-38824586
ABSTRACT

BACKGROUND:

Intussusception, a common cause of abdominal pain in children, often lacks clear underlying causes and is mostly idiopathic. Recurrence, though rare, raises clinical concerns, with rates escalating after each episode. Factors like pathological lead points and Henoch-Schönlein purpura (HSP) are associated with recurrent cases. On the other hand, the prevalence of Helicobacter pylori (H. pylori), often asymptomatic, in children has been declining. Although its infection is reported to be linked with HSP, its role in recurrent intussusception remains unexplored. Further research is needed to understand the interplay among H. pylori (culprit pathogen), HSP (trigger), and intractable intussusception so as to develop effective management strategies. CASE PRESENTATION A two-year-old girl experienced four atypical episodes of intussusception at distinct locations, which later coincided with HSP. Despite treatment with steroids, recurrent intussusception persisted, suggesting that HSP itself was not a major cause for intractable presentations. Subsequent identification of H. pylori infection and treatment with triple therapy resulted in complete resolution of her recalcitrant intussusception.

CONCLUSION:

This instructive case underscored a sequence wherein H. pylori infection triggered HSP, subsequently resulting in recurrent intussusception. While H. pylori infection is not common in young children, the coexistence of intractable intussusception and steroid-resistant recurrent HSP necessitates consideration of H. pylori infection as a potential underlying pathogen.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Gut Pathog Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Gut Pathog Year: 2024 Document type: Article Affiliation country:
...