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Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9.
Gewurz, Benjamin; Guo, Rui; Lim, Matthew; Shah, Hardik; Paulo, Joao; Zhang, Yuchen; Yang, Haopeng; Wang, Liang Wei; Strebinger, Daniel; Smith, Nicolas; Li, Meng; Leong, Merrin; Lutchenkov, Michael; Liang, Jin-Hua; Li, Zhixuan; Wang, Yin; Puri, Rishi; Melnick, Ari; Green, Michael; Asara, John; Papathanassiu, Adonia; Gygi, Steven; Mootha, Vamsi.
Affiliation
  • Gewurz B; Brigham and Women's Hospital.
  • Guo R; Tufts University.
  • Lim M; Department of Cell Biology, Harvard Medical School.
  • Shah H; The University of Chicago.
  • Paulo J; Harvard Medical School.
  • Zhang Y; Brigham and Women's Hospital.
  • Yang H; Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center.
  • Wang LW; Agency for Science, Technology and Research (A*STAR).
  • Strebinger D; Broad Institute.
  • Smith N; Brigham and Women's Hospital.
  • Li M; Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine.
  • Leong M; Brigham and Women's Hospital.
  • Lutchenkov M; Brigham and Women's Hospital.
  • Liang JH; Brigham and Women's Hospital.
  • Li Z; Tufts University.
  • Wang Y; Brigham and Women's Hospital.
  • Puri R; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University.
  • Melnick A; Weill Cornell Medicine.
  • Green M; Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center.
  • Asara J; Department of Pathology.
  • Papathanassiu A; Ergon Pharmaceuticals, LLC, P.O. Box 1001.
  • Gygi S; Harvard University.
  • Mootha V; Massachusetts General Hospital / HHMI.
Res Sq ; 2024 May 30.
Article in En | MEDLINE | ID: mdl-38854072
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Res Sq Year: 2024 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Res Sq Year: 2024 Document type: Article Country of publication: