Downstaging strategies for unresectable hepatocellular carcinoma.
World J Gastroenterol
; 30(20): 2731-2733, 2024 May 28.
Article
in En
| MEDLINE
| ID: mdl-38855157
ABSTRACT
A significant number of patients with hepatocellular carcinoma (HCC) are usually diagnosed in advanced stages, that leads to inability to achieve cure. Palliative options are focusing on downstaging a locally advanced disease. It is well-supported in the literature that patients with HCC who undergo successful conversion therapy followed by curative-intent surgery may achieve a significant survival benefit compared to those who receive chemotherapy alone or those who are successfully downstaged with conversion therapy but not treated with surgery. Hepatic artery infusion chemotherapy can be a potential downstaging strategy, since recent studies have demonstrated excellent outcomes in patients with colorectal liver metastatic disease as well as primary liver malignancies.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Infusions, Intra-Arterial
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Carcinoma, Hepatocellular
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Liver Neoplasms
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Neoplasm Staging
Limits:
Humans
Language:
En
Journal:
World J Gastroenterol
/
World j. gastroenterol
/
World journal of gastroenterology
Journal subject:
GASTROENTEROLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: