Boron-mediated one-pot access to salicylaldehydes via ortho-C-H hydroxylation of benzaldehydes.
RSC Adv
; 14(28): 19922-19925, 2024 Jun 18.
Article
in En
| MEDLINE
| ID: mdl-38903668
ABSTRACT
A novel protocol has been devised for the ortho-C-H hydroxylation of benzaldehydes. Directed by a transient imine group, the borylation of benzaldehydes, sequentially followed by the hydroxylation, furnishes diverse salicylaldehydes in a one-pot manner. The resultant salicylaldehydes could be readily applied in the downstream synthesis to produce bioactive molecules.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
RSC Adv
Year:
2024
Document type:
Article
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