A Prospective, Multicenter, Evaluator-Blinded, Randomized Study of Diluted Calcium Hydroxylapatite to Treat Decollete Wrinkles.
J Drugs Dermatol
; 23(7): 551-556, 2024 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-38954627
ABSTRACT
BACKGROUND:
Calcium hydroxylapatite (CaHA) dermal filler is used for a variety of aesthetic treatments; however, the safety and effectiveness of diluted CaHA for the treatment of décolleté wrinkles have not been established.OBJECTIVE:
To demonstrate the effectiveness and safety of diluted CaHA (Radiesse; 12 CaHAsaline) injection for the improvement of décolleté wrinkles in females.METHODS:
Eligible females with moderate or severe ratings on the Merz Aesthetic Scale (MAS) Decollete Wrinkles - At Rest received up to 3 injection cycles of diluted CaHA either 8 weeks apart (3 injection cycles) or 16 weeks apart (2 injection cycles). Effectiveness was evaluated by improvement on the MAS. Adverse events were recorded over a 52 week period.RESULTS:
Sixteen weeks after the last treatment, the response rate (1-point improvement or greater) on the MAS Decollete Wrinkles - At Rest was 73.5% (P<0.0001; pooled sample) for all patients. The use of diluted CaHA in the decollete also demonstrated a favorable safety profile.CONCLUSIONS:
Diluted CaHA is a safe and effective treatment for the improvement of decollete wrinkles in females.J Drugs Dermatol. 2024;23(7)551-556. doi10.36849/JDD.8261.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Aging
/
Durapatite
/
Dermal Fillers
Limits:
Adult
/
Aged
/
Female
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Humans
/
Middle aged
Language:
En
Journal:
J Drugs Dermatol
Journal subject:
DERMATOLOGIA
Year:
2024
Document type:
Article
Country of publication: