Ichthyosis uteri complicated by endometrial adenocarcinoma with transitional cell differentiation: A case report.
Medicine (Baltimore)
; 103(28): e38792, 2024 Jul 12.
Article
in En
| MEDLINE
| ID: mdl-38996162
ABSTRACT
RATIONALE Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare. PATIENT CONCERNS A 68-year-old woman has been experiencing sporadic, minor vaginal hemorrhages for a few months. The gynecological evaluation revealed a uterine enlargement and imaging demonstrated an irregular mass within the uterus. DIAGNOSIS Endometrial adenocarcinoma with transitional cell differentiation; ichthyosis uteri with dysplasia. INTERVENTIONS:
Radical hysterectomy with pelvic lymphadenectomy was performed followed by postoperative radiotherapy.OUTCOMES:
Postoperative follow-up at 8 months showed a favorable outcome without signs of recurrence and metastasis. LESSONS Adequate pathological sampling is crucial to identifying the accompanying lesions of ichthyosis uteri. Finding molecular alterations in various pathological morphologies is important to understand the evolution of disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adenocarcinoma
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Endometrial Neoplasms
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Hysterectomy
/
Ichthyosis
Limits:
Aged
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Female
/
Humans
Language:
En
Journal:
Medicine (Baltimore)
Year:
2024
Document type:
Article
Affiliation country: