[Pharmaokinetics of beta-escin after administration of various Aesculus extract containing formulations]. / Pharmakokinetik von beta-Aescin nach Gabe verschiedener Aesculus-Extrakt enthaltender Formulierungen.
Pharmazie
; 51(8): 577-81, 1996 Aug.
Article
in De
| MEDLINE
| ID: mdl-8975251
ABSTRACT
With a specific radioimmunoassay the pharmacokinetics and relative bioavailability of escin was measured after administration of different formulations containing Aesculus-extract. Of special interest was the relative bioavailability of escin after administration of a newly developed film-coated tablet with sustained release in comparison to a reference formulation. In a cross-over steady-state study in 24 volunteers bioequivalence of test and reference preparation could be demonstrated. The 90% confidence interval of the AUC (O-tau) was 98.3 to 120.9%.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plants, Medicinal
/
Escin
Type of study:
Clinical_trials
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
De
Journal:
Pharmazie
Journal subject:
FARMACIA
Year:
1996
Document type:
Article
Affiliation country: