Effect of high glucose on expression of MIP-2 and MCP-1 in macrophages cultured in vitro / 上海第二医科大学学报
Article
in Zh
| WPRIM
| ID: wpr-640782
Responsible library:
WPRO
ABSTRACT
0.05).The protein and mRNA expression of MIP-2 in high glucose group significantly increased after culture for 4 h,and guadually decreased then.The protein and mRNA expression of MCP-1 began to increase significantly after culture for 8 h,reached peak at 12 h,and slightly decreased after culture for 24 and 48 h. Conclusion High glucose promotes the protein and mRNA expression of MIP-2 and MCP-1 from mouse peritoneal macrophages cultured in vitro,which indicates that high glucose may delay the wound healing by increasing the expression of chemokines in diabetic mice.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of Shanghai Jiaotong University(Medical Science)
Year:
2006
Document type:
Article