In-Hospital Management and Long-term clinical outcomes and adherence in patients with acute decompensated heart failure: primary results of the first brazilian registry of heart failure (BREATHE)
J. card. fail
; ago.2023. graf
Article
de En
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1509813
Bibliothèque responsable:
BR79.1
ABSTRACT
BACKGROUND:
Heart failure (HF), a common cause of hospitalization, is associated with poor short-term clinical outcomes. Little is known about the long-term prognosis of patients with HF in Latin America.METHODS:
BREATHE was the first nationwide prospective observational study in Brazil that included patients hospitalized due to acute HF. Patients were included during 2 time periods February 2011-December 2012 and June 2016-July 2018. In-hospital management and 12-month clinical outcomes were assessed, and adherence to evidence-based therapies was evaluated.RESULTS:
A total of 3013 patients were enrolled at 71 centers in Brazil. At hospital admission, 83.8% had clear signs of pulmonary congestion. The main cause of decompensation was poor adherence to HF medications (27.8%). Among patients with reduced ejection fraction, concomitant use of beta-blockers, renin-angiotensin-aldosterone inhibitors, and spironolactone numerical decreased from 44.5% at hospital discharge to 35.2% at 3 months. The cumulative incidence of mortality at 12 months was 27.7%, with 24.3% readmission at 90 days and 44.4% at 12 months.CONCLUSIONS:
In this large national prospective registry of patients hospitalized with acute HF, rates of mortality and readmission were higher than those reported globally. Poor adherence to evidence-based therapies was common at hospital discharge and 12 months of follow-up.
Texte intégral:
1
Collection:
06-national
/
BR
Base de données:
CONASS
/
SES-SP
/
SESSP-IDPCPROD
Type d'étude:
Observational_studies
/
Prognostic_studies
Pays/Région comme sujet:
America do sul
/
Brasil
Langue:
En
Journal:
J. card. fail
Année:
2023
Type de document:
Article