A non-enteric adenovirus A12 gastroenteritis outbreak in Rio de Janeiro, Brazil
Mem. Inst. Oswaldo Cruz
; 111(6): 403-406, June 2016. tab, graf
Article
de En
| LILACS
| ID: lil-784253
Bibliothèque responsable:
BR1.1
ABSTRACT
A gastroenteritis outbreak that occurred in 2013 in a low-income community in Rio de Janeiro was investigated for the presence of enteric viruses, including species A rotavirus (RVA), norovirus (NoV), astrovirus (HAstV), bocavirus (HBoV), aichivirus (AiV), and adenovirus (HAdV). Five of nine stool samples (83%) from patients were positive for HAdV, and no other enteric viruses were detected. Polymerase chain reaction products were sequenced and subjected to phylogenetic analysis, which revealed four strains and one strain of non-enteric HAdV-A12 and HAdV-F41, respectively. The HAdV-A12 nucleotide sequences shared 100% nucleotide similarity. Viral load was assessed using a TaqMan real-time PCR assay. Stool samples that were positive for HAdV-A12 had high viral loads (mean 1.9 X 107 DNA copies/g stool). All four patients with HAdV-A12 were < 25 months of age and had symptoms of fever and diarrhoea. Evaluation of enteric virus outbreaks allows the characterisation of novel or unique diarrhoea-associated viruses in regions where RVA vaccination is routinely performed.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
LILACS
Sujet principal:
Adenoviridae
/
Infections à Adenoviridae
/
Gastroentérite
Limites:
Adult
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Pays/Région comme sujet:
America do sul
/
Brasil
Langue:
En
Journal:
Mem. Inst. Oswaldo Cruz
Sujet du journal:
MEDICINA TROPICAL
/
PARASITOLOGIA
Année:
2016
Type de document:
Article
Pays d'affiliation:
Brésil