Variability of epileptiform activity in long-term EEGs with short and long intervals in children with epilepsy.
Clin Neurophysiol
; 111(1): 128-33, 2000 Jan.
Article
de En
| MEDLINE
| ID: mdl-10656521
ABSTRACT
OBJECTIVE:
To evaluate the impact of the time factor on the amount of epileptiform activity in long-term EEG recordings in children with epilepsy.METHODS:
Ten children with epilepsy of different types underwent three 24 h EEG examinations during two consecutive days and with a month's interval. The number of epileptiform discharges during selected corresponding periods of time was counted.RESULTS:
The number of epileptiform discharges on three repeated examination days showed no significant difference (ANOVA P = 0.88) as intraindividual increases and decreases on different days counterbalanced each other within the group. However the standard deviations of the relative changes were larger between recordings with a month's interval compared to those for consecutive days (86% and 33%). The mean magnitude of change was 55% between days separated by a month compared to 24% on consecutive days. The difference was non-significant but showed a trend towards larger changes with a longer interval (P = 0.07).CONCLUSIONS:
The variability of epileptiform activity was larger when the interval between recordings was 1 month compared to consecutive days. The magnitude of the relative changes between intervals of 1 and 30 days showed a trend towards a difference although not statistically significant. When evaluating repeated long-term EEGs in relation to therapy in children, these variations should be considered.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Épilepsies partielles
/
Épilepsie généralisée
/
Électroencéphalographie
Limites:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Langue:
En
Journal:
Clin Neurophysiol
Sujet du journal:
NEUROLOGIA
/
PSICOFISIOLOGIA
Année:
2000
Type de document:
Article
Pays d'affiliation:
Suède